White Shaker Dog Syndrome
White Shaker Dog Syndrome is characterized  by generalized tremor occurring young, predominantly small
dogs. Because this syndrome was initially seen in larger numbers of dogs with white coats, the name White
Shaker Dog Syndrome has also been used to describe it. Maltese and West Highland White Terriers are
commonly affected.

The Association between the disease and dogs with white coats has been curious. Some have suggested that
because melanin, a skin and hair pigment, and some are formed in the body from the same product
{tyrosine}, these dogs may be predisposed to the tremors due to abnormality in tyrosine metabolism. It is
impossible to realize, however,that breeds of other colors may also have a similar problem, including
Yorkshire Terriers, Australian Silky Terriers and Miniature Pinchers. So much for the melanin theory.

Dogs with this disease have a fine tremor of the entire body. Young dogs{9 months to 3 years old} of either
sex are most frequently affected. The tremor is usually persistent throughout the day and will worsen with
handling and excitement. The magnitude of the tremor may increase or remain persistent without therapy.
Other clinical signs associated with neurological system abnormality, such as head tilts, limb weakness and
seizures, and are occasionally seen.

This disease is most often associated with a mild central nervous system inflammation. This inflammation
commonly affects the cerebellum, and dysfunction of this part of the brain may be one of the initiators of the
tremor. Brain inflammation is determined diagnostically by looking at a sample of cerebrospinal fluid under
the microscope. In an affected dog, this fluid contains increased numbers of, white blood cells with normal
to mildly elevated protein concentrations.

White Shaker Dog Syndrome is usually treated effectively with corticosteroids. The corticosteroids are
given in relatively high dosages initially, and then the dose is decreased as the clinical signs may return.

Many dogs, after being treated for three to six months with corticosteroids, may be normal and may not
require additional treatment. Some dogs may require low dosages of corticosteroids every day to keep
clinical signs under control. Overall, the disease is rarely fatal.

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Please if you believe your dog has a problem, seek the advise of your vet. I am personally not familiar with
this disease and can not help you.

A special thanks to Stephen for allowing me to copy this article on my website. Many problems in dogs are
common. The Westie Site is a wonderful informational site and i highly recommend that you visit it.
Stephen
Westie Rescue
PO Box 342
Dunn Loring, VA 22027
703-671-1039 24 Hour Hot line
www.WestieRescue.com
stephen@westierescue.com